Filippo Crea
For the podcast associated with this article, please visit https://academic-oup-com.libproxy.ucl.ac.uk/eurheartj/pages/Podcasts . This Focus Issue on cardio-oncology, heart failure and cardiomyopathies, and digital health and innovation contains the review ‘Use of new and emerging cancer drugs: what the cardiologist needs to know’ by ...
Latest articles
Editorial
RNA and the emerging potential of bio-inspired molecules in cardiovascular disease therapiesNoreen Ahmed and Darryl R Davis
European Heart Journal, ehae348, https://doi-org.libproxy.ucl.ac.uk/10.1093/eurheartj/ehae348
This editorial refers to ‘Non-coding RNA yREX3 from human extracellular vesicles exerts macrophage-mediated cardioprotection via a novel gene-methylating mechanism, by A. Ciullo et al ., https://doi-org.libproxy.ucl.ac.uk/10.1093/eurheartj/ehae357 . Despite decades of work, heart failure remains a global problem, claiming millions of lives ...
Editorial
Sex-related differences in degenerative mitral regurgitation: a call to actionRebecca T Hahn
European Heart Journal, ehae360, https://doi-org.libproxy.ucl.ac.uk/10.1093/eurheartj/ehae360
This editorial refers to ‘Degenerative mitral regurgitation due to flail leaflet: sex-related differences in presentation, management, and outcomes’, by J.F. Avierinos et al., https://doi-org.libproxy.ucl.ac.uk/10.1093/eurheartj/ehae265 . The most common cause of chronic primary mitral regurgitation (MR) in Europe and the USA is mitral ...
Editorial
Inflammation in cardio-oncology: beyond immunotherapiesAnne Lise Ferrara and others
European Heart Journal, ehae333, https://doi-org.libproxy.ucl.ac.uk/10.1093/eurheartj/ehae333
This editorial refers to ‘Rescue of cardiac dysfunction during chemotherapy in acute myeloid leukaemia by blocking IL-1α’, by X. Zhou et al ., https://doi-org.libproxy.ucl.ac.uk/10.1093/eurheartj/ehae188 . The link between metabolic alterations and cardiac dysfunction has been extensively studied for decades, 1–3 arguably reaching its ...
Research Article
Non-coding RNA yREX3 from human extracellular vesicles exerts macrophage-mediated cardioprotection via a novel gene-methylating mechanismAlessandra Ciullo and others
European Heart Journal, ehae357, https://doi-org.libproxy.ucl.ac.uk/10.1093/eurheartj/ehae357
Background and Aims Extracellular vesicles (EVs) secreted by cardiosphere-derived cells exert immunomodulatory effects through the transmission of small non-coding RNAs. Methods The mechanism and role of yREX3, a small Y RNA abundant in EVs in myocardial injury, was investigated. Results yREX3 attenuates cardiac ischaemic ...
Research Article
Therapy duration and improvement of ventricular function in de novo heart failure: the Heart Failure Optimization studyChristian Veltmann and others
European Heart Journal, ehae334, https://doi-org.libproxy.ucl.ac.uk/10.1093/eurheartj/ehae334
Background and Aims In patients with de novo heart failure with reduced ejection fraction (HFrEF), improvement of left ventricular ejection fraction (LVEF) is expected to occur when started on guideline-recommended medical therapy. However, improvement may not be completed within 90 days. Methods Patients with HFrEF and ...
Editorial
Accelerated high sensitivity troponin diagnostics: ready for an even faster pace?Evangelos Giannitsis and others
European Heart Journal, ehae344, https://doi-org.libproxy.ucl.ac.uk/10.1093/eurheartj/ehae344
This editorial refers to ‘Point–of–care high–sensitivity cardiac troponin in suspected acute myocardial infarction assessed at baseline and 2 h by L. Cullen et al ., https://doi-org.libproxy.ucl.ac.uk/10.1093/eurheartj/ehae343 . High sensitivity cardiac troponin (hs-cTn) assays were introduced into clinical routine almost 15 years ago. 1 ...
Editorial
Challenge–skill balance in cardiac surgery: an attempt to explain sex-related differences in coronary surgeryTorsten Doenst and Gloria Faerber
European Heart Journal, ehae350, https://doi-org.libproxy.ucl.ac.uk/10.1093/eurheartj/ehae350
This editorial refers to ‘Multiple arterial versus single arterial coronary artery bypass grafting: sex-related differences in outcomes’, by J. Ren et al ., https://doi-org.libproxy.ucl.ac.uk/10.1093/eurheartj/ehae294 . It is currently debated whether women receive inferior care compared with men in the cardiovascular arena. Coronary ...
Editorial
Brugada syndrome: can polygenic risk scores help the clinician?Elijah R Behr
European Heart Journal, ehae364, https://doi-org.libproxy.ucl.ac.uk/10.1093/eurheartj/ehae364
This editorial refers to ‘Brugada syndrome in Japan and Europe: a genome-wide association study reveals shared genetic architecture and new risk loci’, by T. Ishikawa et al ., https://doi-org.libproxy.ucl.ac.uk/10.1093/eurheartj/ehae251 . Brugada syndrome (BrS) is a heritable disorder predisposing to sudden cardiac arrest (SCA) and sudden ...
Research Article
Evinacumab in hom*ozygous familial hypercholesterolaemia: long-term safety and efficacyDaniel Gaudet and others
European Heart Journal, ehae325, https://doi-org.libproxy.ucl.ac.uk/10.1093/eurheartj/ehae325
Background and Aims hom*ozygous familial hypercholesterolaemia (HoFH) is a rare genetic disorder characterized by severely elevated LDL cholesterol (LDL-C) and premature atherosclerotic cardiovascular disease. In the pivotal Phase 3 HoFH trial (NCT03399786), evinacumab significantly decreased LDL-C in patients with HoFH. ...
Editorial
ANGPTL3 as a therapeutic target for treating hom*ozygous familial hypercholesterolaemia: a shot in the arm for evinacumabGerald F Watts and others
European Heart Journal, ehae321, https://doi-org.libproxy.ucl.ac.uk/10.1093/eurheartj/ehae321
This editorial refers to ‘Long-term safety and effiacy of evinacumab in patients with hom*ozygous familial hypercholesterolaemia’, by D. Gaudet et al ., https://doi-org.libproxy.ucl.ac.uk/10.1093/eurheartj/ehae325 . hom*ozygous familial hypercholesterolaemia (HoFH) is an ultra rare, co-dominantly inherited condition characterized by marked ...
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JOURNAL CITATION INDICATOR
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CARDIAC & CARDIOVASCULAR SYSTEMS
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IMPACT FACTOR
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Editor-in-ChiefProfessor Filippo Crea
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Guidelines
2023 ESC Guidelines for the management of cardiomyopathies
ByElena Arbelo and others
Published: 25 August 2023
2023 ESC Guidelines for the management of endocarditis
ByVictoria Delgado and others
Published: 25 August 2023
2023 ESC Guidelines for the management of cardiovascular disease in patients with diabetes
By Nikolaus Marx and others
Published: 25 August 2023
2023 ESC Guidelines for the management of acute coronary syndromes
By Robert A Byrne and others
Published: 25 August 2023
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